Endocrine Abstracts

We present two patients with unusual manifestations of sarcoidosis and review gonadal involvement in this rare but important disease. A 27 year old man presented to the Ophthalmologists at our hospital with a red eye. He was diagnosed with anterior uveitis and commenced on topical corticosteroids. Following discovery of a testicular mass, he underwent testicular ultrasonography which demonstrated bilateral hyperechoic lesions. Histological examination of an open surgical biops...

Studies on the lipid emulsion for total parenteral nutrition (TPN) for the premature human infant are limited. We investigated the effects of modifying the fatty acid composition of TPN on the growth and development of the preterm piglet.Piglets delivered by Caesarean section on day 112 of gestation (term = 115 days) received an enteral diet (E: n=6) or TPN solution plus Intralipid (54% 18:2, 25% 18:1; I: n=6) or ClinOleic (17% 18:2, 65% 18:1; C: n=6) fo...

We have previously shown that premature piglets maintained on TPN develop fatty livers, but the underlying mechanisms associated with this response in unknown. The aim of the experiment was to use a piglet model for the premature human neonate on TPN to investigate lipase activity in key tissues.Piglets were delivered, by Caesarean, two days prematurely. Bilateral jugular catheters were surgically inserted within 6 hours of birth. Six control piglets wer...